Given the interest in producing proteins and/or glycoproteins with various functionalties at a commercial scale and the expertise and infrastructure at Plant Research International (PRI) in glycomics and proteomics, we are potential collaborators in the development of novel proteins and glycoproteins.
Proteomics analyses add to characterization at the genomics level in that it gives direct confirmation of how native or newly introduced genes are expressed. Expression includes their modes of post-translational modifications, which are of high relevance for biological activity and stability. Since glycoproteins are often the ultimate metabolic end product of genetic expression proteomics analyses provide information which will remain inaccessible for regular genomics and transcriptomics strategies.
In the recent past, PRI has developed strategies to produce plants and plant cell cultures from various origins and transformed with different gene constructs. Characterization of these plant materials requires that the analysis for quantity and quality of the (glyco)proteins is performed at a (semi) high throughput scale.
» Brochure: "Proteins make the difference"
» Flyer: "Glycoproteomics and glycoprotein quality"
» Flyer: "Proteomics: deciphering complex protein mixtures from biological materials"